Thermo Fisher Scientific TRIM71 Polyclonal Antibody
TRIM71 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로 1 mg/mL 농도. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIM71 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human TRIM71 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153657 |
Product Specific Information
- A suggested positive control is human brain tissue lysate.
- PA5-21011 can be used with blocking peptide PEP-1125.
- Antibodies should not be exposed to prolonged high temperatures.
Target Information
TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein important in postembryonic development, and functions downstream of both Shh and Fgf signaling pathways.
Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and likely plays a role in mammalian development.
Recent studies indicate that TRIM71 acts as an E3 ubiquitin ligase and interacts with Dicer and Argonaute proteins (Ago1, Ago2, Ago4). Overexpression or depletion of TRIM71 alters Ago2 protein levels, suggesting regulation of Ago2 turnover.
TRIM71 also cooperates with the pluripotency factor Lin-28 in regulating let-7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.