Thermo Fisher Scientific Selenoprotein W Polyclonal Antibody
Rabbit polyclonal antibody specific for mouse Selenoprotein W. Validated for WB, ELISA, and IP applications. High purity, 1 mg/mL liquid form, stored at -20°C. Cross-reactive with rat and partially with human SelW. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 – 1:5,000 |
| ELISA | 1:100,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with recombinant full-length mouse Selenoprotein W (SelW) protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot and refreeze at -20°C or below for long-term storage.
- Avoid repeated freeze/thaw cycles.
- Centrifuge if solution is not clear after standing.
- Stable for several weeks at 4°C as undiluted liquid.
- Dilute immediately before use.
This antibody is specific for mouse Selenoprotein W.
A BLAST analysis suggests cross-reactivity with rat SelW (98% homology) and partial reactivity with human SelW (87% homology).
Cross-reactivity with other species has not been determined.
Target Information
Selenoprotein W is a selenoprotein containing a selenocysteine (Sec) residue encoded by the UGA codon.
The 3' UTR of selenoprotein mRNA includes a SECIS element required for Sec incorporation.
This protein is highly expressed in skeletal muscle, heart, and brain, belonging to the SelWTH family with a thioredoxin-like fold and conserved CxxU motif, suggesting a redox function.
In mice, Selenoprotein W is involved in muscle growth, differentiation, and neuronal protection from oxidative stress.
A retroprocessed pseudogene for this locus exists on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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