Thermo Fisher Scientific ERN1 Monoclonal Antibody (5F3)
Human ERN1 단백질을 인식하는 Mouse monoclonal antibody (Clone 5F3). Western blot 및 ELISA 검증 완료. Affinity chromatography로 정제된 액상 항체로, PBS(pH 7.4) buffer에 보존제 없이 제공. -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5F3 |
| Immunogen | ERN1 (AAC25991, 401 a.a. ~ 500 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
EEVINLVDQT SENAPTTVSR DVEEKPAHAP ARPEAPVDSM LKDMATIILS TFLLIGWVAF
IITYPLSMHQ QQQLQHQQFQ KELEKIQLLQ QQQQQLPFHPTarget Information
ERN1 (endoplasmic reticulum to nucleus signaling 1) is a serine/threonine kinase and endoribonuclease that mediates ER stress signaling. It acts as a sensor for unfolded proteins in the ER and transmits the unfolded protein response (UPR) by splicing XBP1 mRNA into an active transcriptional activator. ERN1 is essential for fetal viability and cell survival under ER stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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