Thermo Fisher Scientific PTP alpha Polyclonal Antibody
PTP alpha 단백질을 인식하는 Rabbit Polyclonal Antibody. WB, IHC, ELISA, IP 등 다양한 응용에 사용 가능. Human, Mouse, Rat에 반응. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공. -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 650–700 of human Receptor-type tyrosine-protein phosphatase Alpha (PTPRA, UniProt ID: P18433-5) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Phosphorylation of receptors by protein kinases can be reversed by protein phosphatases. The balance between kinases and phosphatases allows cells to switch between phosphorylated and dephosphorylated states in response to stimuli. Dysregulation of this balance may lead to abnormal cell growth associated with cancer and developmental disorders. Protein phosphatases, though generally less substrate-specific, play a key role in controlling dephosphorylation and turnover of phosphoproteins, thus coordinating various signaling pathways and physiological responses.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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