Thermo Fisher Scientific PTPD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (IHC)

1:50-1:250

-

ELISA (ELISA)

1:10,000

-

Immunoprecipitation (IP)

1:50-1:250

-

Product Specifications

Species Reactivity

Rat, Chicken, Human, Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 400-500 on mouse PTPND1 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPN21,uniProtId:Q62136-1,ncbiNodeId:10090,antigenRange:400-500,antigenLength:1176,antigenImageFileName:PTPN-101AP_PTPN21_Q62136-1_Rabbit.svg,antigenImageFileNamePDP:PTPN-101AP_PTPN21_Q62136-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PTPN21 (protein tyrosine phosphatase, non-receptor type 21), also known as PTPD1 or PTPRL10, is a 1,174 amino acid member of the PTP family and localizes to both the cytoplasm and the cytoskeleton. Containing one FERM domain and one tyrosine-protein phosphatase domain, PTPN21 functions to catalyze the water-dependent conversion of a protein tyrosine phosphate into a protein tyrosine and a free phosphate and, via this catalytic activity, may be involved in liver regeneration and spermatogenesis. The gene encoding PTPN21 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.