Thermo Fisher Scientific Phospho-ATF2 (Tyr69, Thr71) Recombinant Superclonal Antibody (24HCLC)

Applications

Western Blot (WB)

• Tested Dilution: 1–2 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Dog, Sheep, and Bovine.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and consistency of monoclonal antibodies.
Each lot can be reproduced identically, eliminating biological variability found in polyclonal antibody production.
Formerly called “Recombinant polyclonal antibody”, this product has been rebranded as “Recombinant Superclonal™ antibody” with no change in performance.

Target Information

ATF-2 (also called CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins.
It interacts with various viral oncoproteins and cellular tumor suppressors and is a target of SAPK/JNK and p38 MAP kinase signaling pathways.
Cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, activates ATF-2 by phosphorylation at Thr69 and Thr71. Both SAPK and p38 MAPK phosphorylate ATF-2 at these sites in vitro and in transfected cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.