Thermo Fisher Scientific CD61 Monoclonal Antibody (VIPL2), APC-Cyanine7
CD61 단백질을 인식하는 마우스 단클론 항체로, APC-Cyanine7 형광으로 결합됨. 인간 및 비인간 영장류 시료에 반응하며 유세포분석(Flow Cytometry)에 적합. 혈소판, 거핵세포 등 다양한 세포에서 CD61 발현 검출에 활용 가능. 4°C 암소 보관, 동결 금지.
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Applications
- Flow Cytometry (Flow): 4 µL/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIPL2 |
| Immunogen | not available |
| Conjugate | APC-Cyanine7 |
| Excitation/Emission Max | 653/782 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898632 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD61, a 90–110 kDa transmembrane glycoprotein of the integrin family. It is expressed on platelets, megakaryocytes, osteoclasts, endothelial cells, and other cell types including leukocytes and smooth muscle cells.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors. It plays a role in platelet aggregation and serves as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin. CD61 associates with either the alpha IIb integrin (CD41) or alpha V integrin (CD51) at the cell surface. It is involved in cell adhesion and cell-surface mediated signaling. Malfunction of CD61 is associated with Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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