Thermo Fisher Scientific CD61 Monoclonal Antibody (VIPL2), PE-Cyanine7
CD61 단백질을 인식하는 마우스 모노클로날 항체로, PE-Cyanine7 형광체로 결합되어 있습니다. 유세포 분석(Flow Cytometry)에 적합하며, 인간 및 비인간 영장류 시료에 반응합니다. 4°C에서 어둡게 보관하며 동결 금지. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 4 µL/1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VIPL2 |
| Immunogen | Not available |
| Conjugate | PE-Cyanine7 |
| Excitation/Emission Max | 569 / 780 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898633 |
Additional Formats
- APC-Cyanine7 (Cat. No. MA5-38720)
- PerCP-Cyanine5.5 (Cat. No. MA5-38722)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD61, a 90–110 kDa transmembrane glycoprotein of the integrin family. CD61 is expressed on platelets, megakaryocytes, osteoclasts, endothelial cells, leukocytes, and smooth muscle cells.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors. It plays a role in platelet aggregation and acts as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. It participates in cell adhesion and signaling processes.
Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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