Thermo Fisher Scientific Phospho-LRRK2 (Ser910) Polyclonal Antibody
인간 LRRK2 단백질의 Ser910 인산화 부위를 인식하는 폴리클로날 항체. WB, IHC, ICC/IF에 적합하며 내인성 인산화 LRRK2 검출에 사용. 고순도 정제, 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human LRRK2 around the phosphorylation site of Ser910 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899234 |
Product Specific Information
Antibody detects endogenous levels of LRRK2 only when phosphorylated at Ser910.
Target Information
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain.
Mutations in LRRK2 have been associated with Parkinson’s disease.
LRRK2 encodes a protein with ankyrin repeat, leucine-rich repeat, kinase, DFG-like motif, RAS, GTPase, MLK-like, and WD40 domains.
The protein is largely cytoplasmic but also associates with the mitochondrial outer membrane.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-114598_LRRK2_Q5S007-1_Rabbit.svg, PA5-114598_LRRK2_Q5S007-1_Rabbit_PDP.jpeg)
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