Thermo Fisher Scientific PNN Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested dilution: 0.2–1 µg/mL
  View 1 publication

Product Specifications

Product Specific Information

• Peptide sequence: MAVAVRTLQE QLEKAKESLK NVDENIRKLT GRDPNDVRPI QARLLALSGP
• Sequence homology:
  Cow: 100%
  Dog: 100%
  Guinea Pig: 100%
  Human: 100%
  Mouse: 100%
  Rabbit: 100%
  Rat: 100%
  Zebrafish: 100%

Target Information

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene (5CAGGTG-3). Capable of reversing CTBP1-mediated transcription repression. Acts as an auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. Participates in the regulation of alternative pre-mRNA splicing and associates to spliced mRNA within 60 nt upstream of the 5`-splice sites. Component of the PSAP complex, which binds RNA in a sequence-independent manner and regulates specific excision of introns in transcription subsets. Involved in epithelial cell-cell adhesion and may function as a potential tumor suppressor for renal cell carcinoma.
[UniProt]

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: PA5-44563_PNN_Q9H307-1_Rabbit.svg, PA5-44563_PNN_Q9H307-1_Rabbit_PDP.jpeg)