Thermo Fisher Scientific PPP1R7 Polyclonal Antibody

Thermo Fisher Scientific PPP1R7 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 0.2–1 µg/mL
Publications: - [References not provided]

Product Specifications

Product Specific Information

Peptide sequence:
QNLIKCIENL EELQSLRELD LYDNQIKKIE NLEALTELEI LDISFNLLRN

Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 100%
Rat: 100%
Zebrafish: 86%

Target Information

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis, and apoptosis. Protein phosphatases are key components of this process. The protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit.

Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360-amino-acid protein localized to the nucleus and contains ten LRR (leucine-rich) repeats. It is expressed in various tissues and functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.