Thermo Fisher Scientific PPP1R7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the middle region of human PPP1R7

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2607758

Product Specific Information

Peptide sequence: QNLIKCIENL EELQSLRELD LYDNQIKKIE NLEALTELEI LDISFNLLRN

Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Target Information

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.