Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 IHC(P) 실험에 적합합니다. 인간 시료에 반응하며, 액상 형태로 제공됩니다. IFITM2와의 교차 반응 가능성이 있습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HNPAPPTSTVIHIRS (aa 36–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933912 |
Product Specific Information
- The immunizing peptide differs by one residue from IFITM2; therefore, cross-reactivity is expected.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM (interferon inducible transmembrane) family. These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play roles in cellular anti-proliferative activities, homotypic cell adhesion, and are often upregulated in cancer cells, suggesting a role in carcinogenesis.
IFITM3, a 133 amino acid membrane protein, is induced by IFN-α and IFN-γ, and its expression can be regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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