Thermo Fisher Scientific IFITM3 Polyclonal Antibody
Human IFITM3 단백질을 인식하는 Goat Polyclonal 항체로, WB 및 IHC(P)에서 검증됨. 비결합형 액상 형태이며 0.5 mg/mL 농도. TBS(pH 7.3, 0.5% BSA) 버퍼에 보관, -20°C에서 보존 권장. 연구용 전용 제품.
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- PA5143274
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence HTVQTFFSPVNS-C (aa 3–14) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933913 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family. These proteins are induced by type I and type II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. They are often upregulated in various cancer cells, suggesting a potential role in carcinogenesis. IFITM3 is a 133 amino acid membrane protein induced by IFN-α and IFN-γ, and its expression can be regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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