Thermo Fisher Scientific SHOX Polyclonal Antibody
SHOX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB와 ELISA에 최적화됨. 인간, 생쥐, 랫드 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태. -20°C 보관, 핵 위치 단백질 검출에 적합.
- 카탈로그번호
- PA5120677
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SHOX Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–110 of human SHOX (NP_000442.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.701 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914249 |
Product Specific Information
- Positive test controls: 293T, BxPC-3, Mouse brain, Rat heart
- Subcellular localization: Nucleus
Immunogen sequence:
NGGGGGGGGK KDSITYREVL ESGLARSREL GTSDSSLQDI TEGGGHCPVH LFKDHVDNDK EKLKEFGTAR VAEGIYECKE KREDVKSEDE D
Target Information
Homeodomain proteins (HP) are transcriptional regulators that coordinate the expression of genes involved in development, differentiation, and cellular transformation. HPs contain a conserved 60-amino-acid domain that binds to regulatory regions of target genes.
SHOX, a member of the bicoid subfamily of the paired homeobox family, controls growth and development and produces two isoforms: SHOXA and SHOXB.
- SHOXA: Expressed in skeletal muscle, placenta, pancreas, heart, and bone marrow fibroblast; lower expression in kidney and lung.
- SHOXB: Highly expressed in osteogenic cells; not expressed in brain, kidney, liver, or lung.
- Defects in SHOX cause Leri-Weill dyschondrosteosis (LWD) and Langer mesomelic dysplasia (LMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-120677_SHOX_O15266-1_Rabbit.svg, PA5-120677_SHOX_O15266-1_Rabbit_PDP.jpeg)
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