Thermo Fisher Scientific Phospho-ATF2 (Thr55, Thr73) Polyclonal Antibody
ATF2 단백질의 Thr55 및 Thr73 인산화 부위를 인식하는 폴리클로날 항체. Western blot, IHC, ICC/IF에 적합. Rabbit 유래, Protein A로 정제된 액상 형태. 세포 스트레스 신호 연구 및 MAPK 경로 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence including phosphorylation sites of threonine 73 or 55 (T-P-T(p)-R-F) derived from human ATF2 and conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | Dulbecco’s PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ATF-2 (also known as CRE-BP1) is a transcription factor that binds to AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins. It interacts with viral oncoproteins and tumor suppressors and is a target of SAPK/JNK and p38 MAP kinase signaling pathways. Cellular stress such as genotoxic agents, cytokines, and UV irradiation can activate ATF-2 through phosphorylation at Thr69 and Thr71, enhancing its transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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