Thermo Fisher Scientific ADORA3 Polyclonal Antibody
Rabbit polyclonal antibody against human Adenosine A3 receptor. Validated for Western blot (1:500–1:3,000). Predicted reactivity with chimpanzee. Provided as liquid form (2.8 mg/mL). Store at 4°C short term or -20°C long term.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Adenosine A3 receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792843 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Chimpanzee (100%)
- Positive Control: MCF-7, mouse brain, rat brain
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Adenosine is involved in various biological processes including urea synthesis, anti-inflammatory response, and inhibition of protein synthesis.
Adenosine receptors (A1-R, A2A-R, A2B-R, A3-R) are G protein-coupled membrane proteins.
- A1-R: Mediates ureagenesis in a partially calcium-dependent manner
- A2A-R: Mediates coronary vasodilation
- A2B-R: Inhibits collagen and total protein synthesis in certain cells
- A3-R: Inhibits TNF-alpha induction and blocks endotoxin CD14 receptor signal transduction pathway
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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