Thermo Fisher Scientific BAMBI Polyclonal Antibody
BAMBI 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BAMBI (Accession Q13145), corresponding to amino acid residues S178–T228 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815657 |
Product Specific Information
Antibody detects endogenous levels of total BAMBI.
Target Information
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane-spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development.
BAMBI transcription is regulated by beta-catenin, BMP, smad3, and smad4.
BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. It is expressed at high levels during odontogenesis and coexpressed with Bmp-4 during early Xenopus embryogenesis. It can also be detected in poorly metastatic human melanoma cell lines.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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