Thermo Fisher Scientific AZIN1 Polyclonal Antibody
AZIN1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며, 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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- PA5100122
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human AZIN1 (Accession O14977), corresponding to amino acid residues A325–V375 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815652 |
Product Specific Information
Antibody detects endogenous levels of total Antizyme inhibitor 1 (AZIN1).
Target Information
Antizyme inhibitor (AZIN1) is a protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake.
AZIN1 is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (OAZ1, OAZ2, OAZ3) on ODC activity by competing with ODC for antizyme binding.
It inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of catalytically active ODC homodimers and restoring polyamine production.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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