Thermo Fisher Scientific SUV39H2 Polyclonal Antibody
SUV39H2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IP, ChIP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 순도(>95%) 보장. 인간, 마우스, 랫트 반응성. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1:50–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human SUV39H2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720758 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) that shares 59% sequence identity with mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, but Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization studies show Suv39h2 enrichment at heterochromatin from the leptotene to round spermatid stage. It specifically accumulates with chromatin of sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with potential epigenetic imprinting to the male germline.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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