Thermo Fisher Scientific CACNA1F Monoclonal Antibody (3B2)
CACNA1F 단백질을 인식하는 Mouse IgG3 단클론 항체로, 인간 시료에 반응합니다. Western blot 및 ELISA에 사용 가능하며, 액상 형태로 제공됩니다. -20°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B2 |
| Immunogen | CACNA1F (NP_005174, 1878–1977 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Tissue culture supernatant |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LHVPGTHSDP SHGKRGSADS LVEAVLISEG LGLFARDPRF VALAKQEIAD ACRLTLDEMD NAASDLLAQG TSSLYSDEES ILSRFDEEDL GDEMACVHAL
Target Information
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are involved in various calcium-dependent processes such as:
- Muscle contraction
- Hormone or neurotransmitter release
- Gene expression
- Cell motility, division, and death
The alpha-1F isoform produces L-type calcium currents, belonging to the high-voltage activated (HVA) group.
These channels are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and omega-agatoxin-IIIA, but are insensitive to omega-conotoxin-GVIA and omega-agatoxin-IVA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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