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Thermo Fisher Scientific CACNA1F Monoclonal Antibody (1H6)
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Thermo Fisher Scientific CACNA1F Monoclonal Antibody (1H6)

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CACNA1F 단백질을 인식하는 Mouse monoclonal antibody(1H6)로, Western blot 및 ELISA에 적합합니다. 인간 유래 단백질에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, 보존제 없이 PBS(pH 7.4)에 보관됩니다.

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pk
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Thermo Fisher Scientific H00000778-M05 CACNA1F Monoclonal Antibody (1H6) 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific CACNA1F Monoclonal Antibody (1H6)

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 1–5 µg/mL
ELISA 10 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG3, kappa
Class Monoclonal
Type Antibody
Clone 1H6
Immunogen CACNA1F (NP_005174, 1878–1977 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa)
Conjugate Unconjugated
Form Liquid
Concentration See Label
Purification Affinity chromatography
Storage Buffer PBS, pH 7.4
Contains No preservative
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

Protein Sequence:

LHVPGTHSDP SHGKRGSADS LVEAVLISEG LGLFARDPRF VALAKQEIAD 
ACRLTLDEMD NAASDLLAQG TSSLYSDEES ILSRFDEEDL GDEMACVHAL

Target Information

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are involved in various calcium-dependent processes such as:

  • Muscle contraction
  • Hormone or neurotransmitter release
  • Gene expression
  • Cell motility, division, and death

The alpha-1F isoform generates L-type calcium currents. Long-lasting (L-type) calcium channels belong to the high-voltage activated (HVA) group.
They are blocked by:

  • Dihydropyridines (DHP)
  • Phenylalkylamines
  • Benzothiazepines
  • Omega-agatoxin-IIIA (ω-Aga-IIIA)

They are insensitive to:

  • Omega-conotoxin-GVIA (ω-CTx-GVIA)
  • Omega-agatoxin-IVA (ω-Aga-IVA)

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

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