Thermo Fisher Scientific CACNA1F Monoclonal Antibody (1H6)
CACNA1F 단백질을 인식하는 Mouse monoclonal antibody(1H6)로, Western blot 및 ELISA에 적합합니다. 인간 유래 단백질에 반응하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, 보존제 없이 PBS(pH 7.4)에 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H6 |
| Immunogen | CACNA1F (NP_005174, 1878–1977 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LHVPGTHSDP SHGKRGSADS LVEAVLISEG LGLFARDPRF VALAKQEIAD
ACRLTLDEMD NAASDLLAQG TSSLYSDEES ILSRFDEEDL GDEMACVHALTarget Information
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are involved in various calcium-dependent processes such as:
- Muscle contraction
- Hormone or neurotransmitter release
- Gene expression
- Cell motility, division, and death
The alpha-1F isoform generates L-type calcium currents. Long-lasting (L-type) calcium channels belong to the high-voltage activated (HVA) group.
They are blocked by:
- Dihydropyridines (DHP)
- Phenylalkylamines
- Benzothiazepines
- Omega-agatoxin-IIIA (ω-Aga-IIIA)
They are insensitive to:
- Omega-conotoxin-GVIA (ω-CTx-GVIA)
- Omega-agatoxin-IVA (ω-Aga-IVA)
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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