Thermo Fisher Scientific CACNA1F Monoclonal Antibody (3B2)
CACNA1F 단백질을 인식하는 Thermo Fisher Scientific의 Mouse monoclonal 항체. Western blot 및 ELISA에 적합하며, 인간 시료에 반응. 액상 형태로 제공되며, 냉동(-20°C) 보관 필요. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B2 |
| Immunogen | CACNA1F (NP_005174, 1878–1977 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LHVPGTHSDP SHGKRGSADS LVEAVLISEG LGLFARDPRF VALAKQEIAD ACRLTLDEMD NAASDLLAQG TSSLYSDEES ILSRFDEEDL GDEMACVHAL
Target Information
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are involved in various calcium-dependent processes such as:
- Muscle contraction
- Hormone or neurotransmitter release
- Gene expression
- Cell motility
- Cell division and cell death
The isoform alpha-1F gives rise to L-type calcium currents.
L-type calcium channels belong to the high-voltage activated (HVA) group and are blocked by:
- Dihydropyridines (DHP)
- Phenylalkylamines
- Benzothiazepines
- Omega-agatoxin-IIIA (ω-Aga-IIIA)
They are insensitive to:
- Omega-conotoxin-GVIA (ω-CTx-GVIA)
- Omega-agatoxin-IVA (ω-Aga-IVA)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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