Thermo Fisher Scientific Phospho-c-Raf (Ser621) Recombinant Superclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Pig, Cat, Bovine, Sheep, and Horse.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of a selection of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, while maintaining the consistency of recombinant production.

Functionally similar to polyclonal antibodies—recognizing multiple epitope sites on the target and providing higher sensitivity for low-abundance targets—these antibodies have a defined mixture of light and heavy chains, ensuring reproducibility across lots.
Formerly known as “Recombinant polyclonal antibody”, this product is now branded as “Recombinant Superclonal™ antibody”. The physical product and performance remain unchanged.

Target Information

Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) functioning downstream of Ras family GTPases. Upon activation, Raf-1 phosphorylates and activates MEK1/2, which subsequently activate ERK1/2. Activated ERKs regulate gene expression involved in cell cycle, apoptosis, differentiation, and migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.