Thermo Fisher Scientific HCN4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

Product Specifications

Published species

Mouse

Host/Isotype

Guinea pig / IgG

Class

Polyclonal

Type

Antibody

Immunogen

GST fusion protein corresponding to amino acid residues 119-155 of human HCN4 (Intracellular, N-terminus) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HCN4,uniProtId:Q9Y3Q4-1,ncbiNodeId:9606,antigenRange:120-155,antigenLength:1203,antigenImageFileName:PA5-111793_HCN4_Q9Y3Q4-1_Guinea_pig.svg,antigenImageFileNamePDP:PA5-111793_HCN4_Q9Y3Q4-1_Guinea_pig_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2857202

Product Specific Information

Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

GST fusion protein sequence is: HGHLHDSAEE RRLIAEGDA SPGEDRTPPG LAAEPERP

Homology: Rabbit amino acid residues identical; rat - 35/37 amino acid residues identical; mouse - 33/37 amino acid residues identical.

Target Information

HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.