Thermo Fisher Scientific HCN4 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitute antibody with 50 µL of double distilled water (DDW).
• Store reconstituted solution at 4°C for up to 1 week.
• For long-term storage, aliquot and keep at -20°C.
• Avoid repeated freeze-thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g for 5 min).

GST fusion protein sequence:
HGHLHDSAEE RRLIAEGDA SPGEDRTPPG LAAEPERP

Homology:

• Rabbit: identical amino acid residues
• Rat: 35/37 residues identical
• Mouse: 33/37 residues identical

Target Information

HCN4 is a member of the hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channel family.
HCN currents are associated with:

• Pacemaker activity in the heart and brain
• Resting potential control
• Neuronal plasticity

HCN4 channels also function as receptors for sour taste and contribute to pacemaker potential generation in the sinoatrial node.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 없음)