Thermo Fisher Scientific MARCO Monoclonal Antibody (PLK-1), PE-Cyanine7, eBioscience
인간 MARCO 단백질을 인식하는 PLK-1 단클론 항체로, PE-Cyanine7 형광 표지된 유세포분석용 시약입니다. 사전 희석되어 사용이 간편하며, 4°C 암소 보관이 필요합니다. 암 미세환경 연구 및 면역세포 분석에 적합합니다.
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Applications
- Flow Cytometry (Flow): 5 µL (0.06 µg)/test
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Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG3 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PLK-1 |
| Immunogen | Human alveolar macrophages |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Concentration | 5 µL / Test |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Wet ice |
| RRID | AB_2762451 |
Additional Formats
Product Specific Information
Description:
This PLK-1 monoclonal antibody recognizes human MARCO (SR-A6, SCARA2).
Applications Reported:
Reported for use in flow cytometric analysis.
Applications Tested:
Pre-diluted and tested by flow cytometric analysis of human monocyte-derived macrophages.
Recommended use: 5 µL (0.06 µg) per test (final volume 100 µL).
Applicable cell number range: 10⁵–10⁸ cells/test.
Light Sensitivity:
This tandem dye is sensitive to photo-induced oxidation. Protect from light.
Fixation:
Samples can be stored in IC Fixation Buffer (Product #00-8222) or 1-step Fix/Lyse Solution (Product #00-5333-34) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Clone-specific performance should be determined empirically.
Excitation / Emission:
488–561 nm / 775 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers.
Target Information
MARCO (Macrophage Receptor with Collagenous Structure):
Also known as SR-A6 or SCARA2, MARCO is a macrophage surface receptor and member of the class A scavenger receptor family.
It binds Gram-negative and Gram-positive bacteria through an extracellular SRCR domain.
The protein forms trimeric structures via collagenous domain association.
Due to its expression in tumor-infiltrating macrophages and immunosuppressive role in tumor microenvironments, MARCO is a potential target for cancer immunotherapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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