Thermo Fisher Scientific MARCO Monoclonal Antibody (PLK-1), PE-Cyanine7, eBioscience

Applications

• Flow Cytometry (Flow): 5 µL (0.06 µg)/test
  View 2 publications

Product Specifications

Additional Formats

• APC
• PE
• Request custom conjugation

Product Specific Information

Description:
This PLK-1 monoclonal antibody recognizes human MARCO (SR-A6, SCARA2).

Applications Reported:
Reported for use in flow cytometric analysis.

Applications Tested:
Pre-diluted and tested by flow cytometric analysis of human monocyte-derived macrophages.
Recommended use: 5 µL (0.06 µg) per test (final volume 100 µL).
Applicable cell number range: 10⁵–10⁸ cells/test.

Light Sensitivity:
This tandem dye is sensitive to photo-induced oxidation. Protect from light.

Fixation:
Samples can be stored in IC Fixation Buffer (Product #00-8222) or 1-step Fix/Lyse Solution (Product #00-5333-34) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Clone-specific performance should be determined empirically.

Excitation / Emission:
488–561 nm / 775 nm
Laser Compatibility: Blue, Green, Yellow-Green lasers.

Target Information

MARCO (Macrophage Receptor with Collagenous Structure):
Also known as SR-A6 or SCARA2, MARCO is a macrophage surface receptor and member of the class A scavenger receptor family.
It binds Gram-negative and Gram-positive bacteria through an extracellular SRCR domain.
The protein forms trimeric structures via collagenous domain association.
Due to its expression in tumor-infiltrating macrophages and immunosuppressive role in tumor microenvironments, MARCO is a potential target for cancer immunotherapy.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지