Thermo Fisher Scientific PSMD2 Polyclonal Antibody
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Thermo Fisher Scientific PSMD2 Polyclonal Antibody는 인간 및 생쥐 반응성을 가지며 Western blot, IHC, IP 등에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of Human Proteasome (Prosome, Macropain) 26S Subunit, non-ATPase, 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
- Based on sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan.
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of two main parts: a 20S core and a 19S regulator.
- The 20S core consists of four rings (two alpha and two beta rings) with 28 non-identical subunits.
- The 19S regulator includes a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent manner.
They play a key role in class I MHC peptide processing and may also participate in TNF signaling pathways.
A pseudogene related to this protein is found on chromosome 1.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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