
Thermo Fisher Scientific PSME1 Polyclonal Antibody
Thermo Fisher Scientific의 PSME1 Polyclonal Antibody는 인간 Proteasome Activator Subunit 1 (PA28 alpha)을 인식하는 Rabbit IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 액상 형태로 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A303858Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PSME1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:5,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 alpha) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Proteolytic degradation is essential for maintaining appropriate levels of short-lived and regulatory proteins involved in cellular metabolism, stress response, antigen presentation, receptor modulation, cell cycle regulation, transcription, and signaling.
The ubiquitin-proteasome pathway degrades most proteins in the eukaryotic cytosol and nucleus, while others are processed via the vacuolar pathway involving endosomes, lysosomes, and the endoplasmic reticulum.
The 26S proteasome is an ATP-dependent, multisubunit complex (~2.5 MDa) composed of a 20S core and 19S regulatory subunits, which recognize ubiquitinated proteins and facilitate their degradation.
Defects in this pathway are associated with genetic diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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