Thermo Fisher Scientific Gemin 3 Polyclonal Antibody
Gemin 3 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제 및 PBS/glycerol buffer 보존. 세포질 및 핵 내 Gemin 3 검출에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 25–280 of human DDX20 (NP_009135.4) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.04 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914522 |
Product Specific Information
Positive test controls include: MCF7, ES-2, 293T, HepG2, HeLa, Mouse spleen, Rat testis, Mouse ovary.
The target is usually found in the following locations: Cytoplasm, Nucleus, gem.
Immunogen sequence:
VQVPAPEPTP GPVRILRTAQ DLSSPRTRTG DVLLAEPADF ESLLLSRPVL EGLRAAGFER PSPVQLKAIP LGRCGLDLIV QAKSGTGKTC VFSTIALDSL VLENLSTQIL ILAPTREIAV QIHSVITAIG IKMEGLECHV FIGGTPLSQD KTRLKKCHIA VGSPGRIKQL IELDYLNPGS IRLFILDEAD KLLEEGSFQE QINWIYSSLP ASKQMLAVSA TYPEFLANAL TKYMRDPTFV RLNSSDPSLI GLKQYY
Target Information
Gemin 3 is a member of the DEAD box protein family characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. These proteins are involved in various RNA-related processes such as translation initiation, splicing, and ribosome assembly.
Gemin 3 is part of the survival of motor neurons (SMN) complex and may play a catalytic role in RNP function.
Dysfunction of Gemin 3 is associated with spinal muscular dystrophy and muscular atrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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