Thermo Fisher Scientific EZH2 Polyclonal Antibody
EZH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ELISA, IP 등 다양한 응용 가능. Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제. -20°C 보관, 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5–4 µg antibody for 200–400 µg extracts |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 133–252 of human EZH2/KMT6 (NP_001190176.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.67 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914517 |
Product Specific Information
- Positive test controls: MCF7, C6, HeLa, Mouse brain
- Subcellular localization: Nucleus
Immunogen sequence:
YMGDEVLDQD GTFIEELIKN YDGKVHGDRE CGFINDEIFV ELVNALGQYN DDDDDDDGDD PEEREEKQKD LEDHRDDKES RPPRKFPSDK IFEAISSMFP DKGTAEELKE KYKELTEQQL
Target Information
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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