Thermo Fisher Scientific SETD7 Monoclonal Antibody (OTI2D10), TrueMAB
SETD7 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체. Western blot, IHC, ICC, Flow Cytometry에 사용 가능. 인간, 생쥐, 랫드, 개에 반응. 동결건조 형태, 1 mg/mL 농도, 보존제 없음. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D10 |
| Immunogen | Full length human recombinant protein of human SETD7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
SETD7 is a histone methyltransferase that specifically monomethylates Lys-4 of histone H3, a marker for epigenetic transcriptional activation.
It plays a key role in activating genes such as collagenase and insulin, recruited by IPF1/PDX-1 to the insulin promoter.
SETD7 also methylates non-histone proteins, including p53/TP53 and TAF10, enhancing their stability and transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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