Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI8G8), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The BAIAP2 protein is a brain-specific angiogenesis inhibitor (BAI1)-binding adaptor protein that links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system.
BAIAP2 associates with Rho small G proteins, contributing to stress fiber formation and cytokinesis. It is involved in lamellipodia and filopodia formation in motile cells, potentially influencing neuronal growth-cone guidance.
Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Multiple transcript variants encoding distinct isoforms are produced by alternative splicing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.