Thermo Fisher Scientific NMNAT1 Monoclonal Antibody (OTI1F7), TrueMAB
NMNAT1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1F7). Western blot 및 Immunocytochemistry에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, PBS buffer(8% trehalose) 내 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F7 |
| Immunogen | Full length human recombinant protein of human NMNAT1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The coenzyme NAD and its derivatives participate in numerous metabolic redox reactions and are involved in protein ADP-ribosylation, histone deacetylation, and Ca²⁺ signaling pathways.
NMNAT (EC 2.7.7.1) is a key enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).
[supplied by OMIM]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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