Thermo Fisher Scientific GPHN Monoclonal Antibody (OTI3B6), TrueMAB
인간 GPHN 단백질을 표적으로 하는 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. 고순도 정제된 형태로 제공되며, 재구성 및 결합 실험에 용이합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B6 |
| Immunogen | Full-length human recombinant protein of human GPHN produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Gephyrin is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high-affinity binding to receptor subunit domains and tubulin dimers.
In non-neuronal tissues, it is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with hyperplexia and molybdenum cofactor deficiency.
Numerous alternatively spliced transcript variants encoding different isoforms have been described, although the full-length nature of all variants is not yet known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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