Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Monoclonal Antibody (rL1C1)
인간 B세포 마커인 Kappa Light Chain을 인식하는 Mouse monoclonal 항체. IHC(P), IHC(PFA), Peptide Array에 사용 가능. Rat에는 반응하지 않음. 단백질 A/G 정제, PBS(pH 7.4) 용액, 보존제 없음. 연구용으로만 사용.
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- 3514MSM12P1ABX
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rL1C1 |
| Immunogen | Human B-Lymphoma Cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Product Specific Information
- Does not react with Rat.
Target Information
Immunoglobulin classes share a basic four-polypeptide chain structure consisting of two heavy chains (five types) and two light chains (kappa, lambda; both with a molecular weight of approximately 22.5 kDa).
Kappa and lambda chains each have variable and constant regions, which can be distinguished by their antigenic properties. The typical ratio of kappa to lambda light chains is 70:30.
Antibodies against the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates a clonal and therefore malignant nature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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