Thermo Fisher Scientific NIPSNAP1 Polyclonal Antibody
NIPSNAP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 용액 형태로 제공되며, 2–8°C 보관이 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid peptide from near the center of human NIPSNAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153538 |
Product Specific Information
A suggested positive control is human brain tissue lysate.
PA5-20501 can be used with blocking peptide PEP-0621.
Target Information
NIPSNAP is a member of an evolutionarily well-conserved gene family and shows strong sequence similarity to a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and a non-neuronal SNAP25-like protein.
Studies indicate NIPSNAP is involved in regulating the Ca²⁺-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents.
Reduced NIPSNAP expression has been observed in the phenylketonuria (PKU) mouse brain, suggesting a potential role in memory.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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