Thermo Fisher Scientific BAP3 Polyclonal Antibody
인간 BAP3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. SK-N-SH cell lysate를 양성 대조군으로 사용할 수 있습니다.
- 카탈로그번호
- PA520498
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 2 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 12 amino acid peptide from near the amino terminus of human BAP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157000 |
Product Specific Information
- A suggested positive control is SK-N-SH cell lysate.
- PA5-20498 can be used with blocking peptide PEP-0618.
Target Information
BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family.
BAP3 is predominantly expressed in the brain and possesses high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release.
Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor.
Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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