Thermo Fisher Scientific AIFM3 Polyclonal Antibody
AIFM3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 2–8°C에서 보관 가능합니다.
- 카탈로그번호
- PA520502
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the amino terminus of human AIFM3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152823 |
Product Specific Information
- Suggested positive control: mouse brain tissue lysate
- PA5-20502 can be used with blocking peptide PEP-0622.
Target Information
Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover as well as tumor formation. AIFM3 (Apoptosis-Inducing Factor, Mitochondria-Associated 3) is a protein similar to AIF and is expressed ubiquitously, mainly localized to the inner mitochondrial membrane. Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis. Overexpression of AIFM3 induces cytochrome c release, caspase 3 cleavage, and apoptosis through caspase activation. Multiple isoforms of AIFM3 exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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