Thermo Fisher Scientific AGK Monoclonal Antibody (9A3B1)
AGK 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 ELISA에 적합. Human AGK(1-422aa) 재조합 단백질을 면역원으로 사용. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- MA534959
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9A3B1 |
| Immunogen | Recombinant fusion protein containing amino acids 1–422 of human AGK (NP_060708.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2848865 |
Product Specific Information
Immunogen sequence:
MTVFFKTLRN HWKKTTAGLC LLTWGGHWLY GKHCDNLLRR AACQEAQVFG NQLIPPNAQV KKATVFLNPA ACKGKARTLF EKNAAPILHL SGMDVTIVKT DYEGQAKKLL ELMENTDVII VAGGDGTLQE VVTGVLRRTD EATFSKIPIG FIPLGETSSL SHTLFAESGN KVQHITDATL AIVKGETVPL DVLQIKGEKE QPVFAMTGLR WGSFRDAGVK VSKYWYLGPL KIKAAHFFST LKEWPQTHQA SISYTGPTER PPNEPEETPV QRPSLYRRIL RRLASYWAQP QDALSQEVSP EVWKDVQLST IELSITTRNN QLDPTSKEDF LNICIEPDTI SKGDFITIGS RKVRNPKLHV EGTECLQASQ CTLLIPEGAG GSFSIDSEEY EAMPVEVKLL PRKLQFFCDP RKREQMLTSP TQ
Target Information
AGK는 monoacylglycerol과 diacylglycerol을 각각 인산화하여 lysophosphatidic acid(LPA)와 phosphatidic acid(PA)를 형성하는 lipid kinase입니다. sphingosine은 인산화하지 않습니다. 과발현 시 LPA의 생성 및 분비를 증가시켜 EGFR의 전이활성화와 MAPK 신호 경로를 활성화하여 세포 성장 증가를 유도합니다.
⚠ WARNING:
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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