Thermo Fisher Scientific Cytokeratin 81/86 Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal 항체로, KRT81/86 단백질을 검출합니다. Western blot 및 IHC(P) 실험에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT86 (Accession O43790), corresponding to amino acid residues V261–H311 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853604 |
Product Specific Information
This antibody detects endogenous levels of total KRT81/86.
Target Information
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein that heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structural similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related, while the other includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with the rare dominant hair disease monilethrix.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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