Thermo Fisher Scientific CYP21A2 Polyclonal Antibody
Rabbit polyclonal antibody against human CYP21A2 for WB and IHC applications. Detects endogenous truncated steroid 21-hydroxylase. Supplied as unconjugated liquid form at 1 mg/mL. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human (unreviewed) CYP21A2 (Accession Q8TE42), corresponding to amino acid residues W50–G70 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816015 |
Product Specific Information
Antibody detects endogenous levels of total truncated steroid 21-hydroxylase.
Target Information
CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in the CYP21A2 gene cause congenital adrenal hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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