Thermo Fisher Scientific RAD23B Monoclonal Antibody (OTI7F11), TrueMAB
Human RAD23B 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, carrier-free 형태로 제공. Lyophilized 제품으로 재구성 후 약 1 mg/mL 농도로 사용 가능. DNA 손상 복구 연구 및 단백질 상호작용 분석에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–253 of human RAD23B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The RAD23B gene encodes one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER).
RAD23B participates in the protein complex that complements the NER defect of xeroderma pigmentosum group C (XP-C) cell extracts in vitro.
It interacts with and enhances the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), suggesting a role in DNA damage recognition during base excision repair.
The protein contains an N-terminal ubiquitin-like domain that interacts with the 26S proteasome, indicating a potential role in the ubiquitin-mediated proteolytic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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