Thermo Fisher Scientific CaV1.2 (CACNA1C) Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size
• Ships as a lyophilized powder at room temperature
• Upon arrival, store at -20°C
• Reconstituted solution: store at 4°C, protected from light, for up to 1 week
• For long-term storage, aliquot and keep at -20°C
• Avoid multiple freeze/thaw cycles
• Centrifuge all antibody preparations before use (10,000 × g, 5 min)

Target Information

Gene: CACNA1C
Protein: CaV1.2 (alpha-1 subunit of voltage-dependent calcium channel)

• Mediates calcium ion influx upon membrane polarization
• Alpha-1 subunit: 24 transmembrane segments forming the ion pore
• Channel complex: alpha-1, alpha-2/delta, beta, gamma subunits (1:1:1:1 ratio)
• Multiple isoforms from different genes or alternative splicing
• Inhibited by dihydropyridine
• Alternative splicing results in various transcript variants

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.