Thermo Fisher Scientific CaVpan alpha 1 Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:200

Product Specifications

Product Specific Information

Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freeze/thaw cycles. Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

Gene: CACNA1C
CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel.
Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization.
The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass.
The calcium channel complex includes alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Multiple isoforms exist, generated by different genes or alternative splicing.
The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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