Thermo Fisher Scientific CaV1.2 (CACNA1C) Polyclonal Antibody
CaV1.2(CACNA1C) 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 연구용으로만 사용.
- 카탈로그번호
- ACC-003-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CaV1.2 (CACNA1C) Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)TTKINMDDLQPSENEDKS, corresponding to amino acid residues 848–865 of rat CaV1.2 (intracellular loop between domains II and III) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size
- Ships as lyophilized powder at room temperature
- Store at -20°C upon arrival
- Reconstituted solution stable at 4°C for up to 1 week
- For long-term storage, aliquot and store at -20°C
- Avoid multiple freeze/thaw cycles
- Centrifuge all antibody preparations before use (10,000 × g, 5 min)
Target Information
CACNA1C encodes the alpha-1 subunit of a voltage-dependent calcium channel. These channels mediate calcium ion influx into cells upon membrane depolarization.
The alpha-1 subunit forms the ion-conducting pore and consists of 24 transmembrane segments.
Calcium channels are composed of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
Multiple isoforms exist due to alternative splicing or distinct genes.
The CACNA1C protein binds to and is inhibited by dihydropyridine.
Alternative splicing results in various transcript variants encoding different proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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