Thermo Fisher Scientific Phospho-JNK1/JNK2/JNK3 (Thr183, Tyr185) Polyclonal Antibody
JNK1/JNK2/JNK3의 Thr183/Tyr185 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상형, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Thr183/Tyr185 (M-M-T(p)-P-Y(p)-V-V) derived from Human JNK1/JNK2/JNK3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2554434 |
Product Specific Information
- Suggested positive control for Western blot: C6 cells
- Suggested positive control for ICC/IF: HeLa cells
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases.
MAPKs are serine-threonine kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development.
JNK pathways are activated by stress and inflammatory signals, and JNK exists in ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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