Thermo Fisher Scientific APOC1 Monoclonal Antibody (2E2-1A3)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Protein sequence:
MRLFLSLPVL VVVLSIVLEG PAPAQGTPDV SSALDKLKEF GNTLEDKARE LISRIKQSEL SAKMREWFSE TFQKVKEKLK IDS

Target Information

Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which modulate the metabolism of triglyceride-rich lipoproteins.

• The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver, activated when monocytes differentiate into macrophages.
• The apoC-II gene encodes a 79 amino acid single-chain protein that acts as a cofactor for lipoprotein lipase, facilitating triglyceride hydrolysis.
• The apoC-III gene, located on chromosome 11q23, encodes a protein that may delay catabolism of triglyceride-rich particles by inhibiting lipoprotein lipase and hepatic lipase.
• The apoC-IV gene, also on chromosome 19q13.2, encodes a 127 amino acid protein primarily expressed in the liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.