Thermo Fisher Scientific CK1 gamma-1 Monoclonal Antibody (OTI1C5)
CK1 gamma-1 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 인간 단백질에 반응하며 연구용으로 적합. 안정한 PBS/BSA/glycerol 저장 버퍼 구성.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 163–422 of CSNK1G1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724150 |
Target Information
Casein kinase I (CKI) and casein kinase II (CKII) are families of serine/threonine protein kinases found in all eukaryotes. CKI family members, including CKI alpha, gamma, epsilon, and delta, are involved in regulating cytoplasmic and nuclear processes such as DNA replication and repair.
CKII typically exists as a tetrameric complex (α₂β₂ or αα′β₂), where the catalytic α subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is elevated in proliferating and differentiating cells and is known to phosphorylate over 100 substrates, including nuclear oncoproteins, transcription factors, and DNA metabolism enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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