Thermo Fisher Scientific CK1 gamma-1 Monoclonal Antibody (OTI1D7)
Human CK1 gamma-1 단백질을 인식하는 Mouse 단일클론 항체로 Western blot 및 IHC(Paraffin) 검증 완료. Unconjugated 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer에 보관. 연구용 시약으로 DNA 복제 및 수리 관련 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 163–422 of CSNK1G1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724151 |
Target Information
Casein kinase I (CKI) and casein kinase II (CKII) are families of serine/threonine protein kinases found in all eukaryotes. CKI members (alpha, gamma, epsilon, delta) regulate cytoplasmic and nuclear processes such as DNA replication and repair. CKII typically forms tetrameric complexes (α2β2 or αα′β2), where the α subunit’s catalytic activity is modulated by the β regulatory subunit. CKII phosphorylates over 100 substrates, including nuclear oncoproteins, transcription factors, and enzymes involved in DNA metabolism. High CKII activity is observed in the cytosol and nucleus of proliferating and differentiating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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