Thermo Fisher Scientific Phospho-TGFBR3 (Thr843) Polyclonal Antibody
TGFBR3 Thr843 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. 고순도 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TGFBR3 (Accession Q03167), corresponding to amino acid residues around phosphorylated Thr843 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817218 |
Product Specific Information
Antibody detects endogenous levels of TGF beta Receptor III only when phosphorylated at Thr843.
Target Information
This locus encodes the transforming growth factor (TGF)-beta type III receptor.
The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members.
Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling.
Decreased expression of this receptor has been observed in various cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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