Thermo Fisher Scientific Phospho-S6 (Tyr209) Polyclonal Antibody
RPS6의 Tyr209 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(P)에서 사용 가능. 인산화된 단백질 수준 분석에 적합하며, PBS/glycerol buffer로 안정화된 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6 (Accession P62753), corresponding to amino acid residues around phosphorylated Tyr209. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817027 |
Product Specific Information
Antibody detects endogenous levels of RPS6 only when phosphorylated at Tyr209.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 distinct proteins. The RPS6 gene encodes a cytoplasmic ribosomal protein that is part of the 40S subunit and belongs to the S6E family. It is a major substrate of ribosomal protein kinases, with phosphorylation occurring at multiple serine residues in response to growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs during growth arrest. This protein may play a role in controlling cell growth and proliferation through selective translation of mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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